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Topotecan hydrochloride
[CAS# 119413-54-6]

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Identification
ClassificationAPI >> Antineoplastic agents >> Natural source antineoplastic agents
NameTopotecan hydrochloride
Synonyms(S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione monohydrochloride; Nogitecan hydrochloride; Hycamtin
Molecular StructureCAS # 119413-54-6, Topotecan hydrochloride
Molecular FormulaC23H23N3O5.HCl;C23H24ClN3O5
Molecular Weight457.91
CAS Registry Number119413-54-6
EC Number601-607-9
Properties
Melting point213-218 °C
Safety Data
Hazard Classification
up    Details
HazardClassCategory CodeHazard Statement
Germ cell mutagenicityMuta.1BH340
CarcinogenicityCarc.1BH350
Reproductive toxicityRepr.1BH360
Acute toxicityAcute Tox.2H300
Chronic hazardous to the aquatic environmentAquatic Chronic3H412
Specific target organ toxicity - single exposureSTOT SE1H370
Reproductive toxicityRepr.2H361
CarcinogenicityCarc.2H351
Acute toxicityAcute Tox.4H302
Specific target organ toxicity - single exposureSTOT SE3H335
Acute toxicityAcute Tox.3H301
Eye irritationEye Irrit.2H319
Skin irritationSkin Irrit.2H315
SDSAvailable
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