2-Chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzenesulfonamide
[CAS# 74658-80-3]

Identification

• Name: 2-Chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzenesulfonamide
• Synonyms: (±)-Chlorthalidone; (±)-Hygroton; 1-keto-3-(3'-sulfamyl-4'-chlorophenyl)-3-hydroxyisoindoline
• Molecular Formula: C₁₄H₁₁ClN₂O₄S
• Molecular Weight: 338.77
• CAS Registry Number: 74658-80-3
• SMILES: C1=CC=C2C(=C1)C(=O)NC2(C3=CC(=C(C=C3)Cl)S(=O)(=O)N)O
• InChI: 1S/C14H11ClN2O4S/c15-11-6-5-8(7-12(11)22(16,20)21)14(19)10-4-2-1-3-9(10)13(18)17-14/h1-7,19H,(H,17,18)(H2,16,20,21)
• InChIKey: JIVPVXMEBJLZRO-UHFFFAOYSA-N

Properties

• Density: 1.6±0.1g/cm³ (Cal.)

Safety Data

• Safety Description: IRRITANT

References

• (1): Nada. S. Abdelwahab. Determination of atenolol, chlorthalidone and their degradation products by TLC-densitometric and chemometric methods with application of model updating, Anal. Methods, 2010, 2, 1994.