Manganese gluconate
[CAS# 6485-39-8]

Identification

• Classification: Food additive >> Nutrition supplements >> Inorganic salts
• Name: Manganese gluconate
• Molecular Formula: (C₆H₁₁O₇)₂.Mn
• Molecular Weight: 445.23
• CAS Registry Number: 6485-39-8
• EC Number: 229-350-4
• SMILES: C([C@H]([C@H]([C@@H]([C@H](C(=O)[O-])O)O)O)O)O.C([C@H]([C@H]([C@@H]([C@H](C(=O)[O-])O)O)O)O)O.[Mn+2]

Properties

• Water solubility: soluable in hot water

Safety Data

• Hazard Symbols: GHS07 Warning
• Risk Statements: H319
• Safety Statements: P264+P265-P280-P305+P351+P338-P337+P317

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Eye irritation	Eye Irrit.	2	H319

Discovery and Applications

Manganese gluconate is the manganese salt of gluconic acid, known for its water solubility and stability. Gluconic acid is derived from glucose and forms a chelate with manganese ions, enhancing its bioavailability and usability in various applications. The compound was first synthesized in the early 20th century and studied for its potential health benefits and industrial applications.

In health and nutrition, manganese gluconate is used as a dietary supplement due to its important role in various enzymatic reactions and biological processes. Manganese is essential for bone formation, metabolism, and antioxidant defense in the human body. Supplemental intake of manganese gluconate is beneficial for overall health, especially for people with inadequate diets or specific health conditions that require manganese supplementation.

Manganese gluconate is widely used in industrial processes, especially in agriculture and water treatment. In agriculture, it is used as a micronutrient fertilizer to promote plant growth and development. Manganese is an important component of plant photosynthesis and enzyme systems, helping to improve crop yields and quality.

In water treatment, manganese gluconate is used as a chelating agent to control manganese levels in drinking water and industrial wastewater. Its chelating properties help prevent manganese deposition and scaling in pipes and water systems, thereby ensuring water quality and infrastructure integrity.

The compound is also used in cosmetic and personal care formulations for its antioxidant properties and skin benefits. Manganese gluconate supports collagen synthesis and skin elasticity and is an important ingredient in anti-aging creams, serums, and skin care products. Incorporating it into hair care products promotes scalp health and hair strength, which improves overall hair vitality.

Manganese gluconate is safe when used in accordance with regulatory guidelines. It is rigorously tested to ensure purity and efficacy in dietary supplements, agricultural products, and personal care formulations. Proper use and dosage recommendations mitigate potential risks associated with manganese toxicity, especially in industrial applications and consumer products.

Manganese gluconate is produced and used in accordance with sustainable practices. Its use in agriculture is intended to optimize soil nutrient utilization and promote efficient crop growth while minimizing environmental impact. As a water treatment agent, it helps maintain water quality standards and sustainable resource management practices.

Ongoing research continues to explore new applications and formulations for manganese gluconate, particularly in health sciences and industrial technologies. Innovations in bioavailability and delivery systems are intended to increase its effectiveness and expand its therapeutic applications, addressing changing consumer preferences and global health challenges.

References

2023. Effects of Zinc-Gluconate Levels on Growth Performance, Whole-Body Composition, and Mineral and Enzyme Activities of Juvenile Mori (Cirrhinus mrigala). Biological Trace Element Research, 201(12).
DOI: 38066311

2024. Minimum inhibitory and bactericidal/fungicidal concentration of commercially available products containing essential oils, zinc gluconate, or 4% chlorhexidine for Malassezia pachydermatis, Pseudomonas aeruginosa, and multi-drug resistant Staphylococcus pseudintermedius canine clinical isolates. Veterinary Research Communications, 48(5).
DOI: 39225973

2024. “The effects of non-surgical periodontal treatment plus zinc and magnesium supplementation on oxidative stress and antioxidants enzymes in type 2 diabetes patients: a quasi-experimental study”. BMC Oral Health, 24(1).
DOI: 11299399